Oruvail (Ketoprofen) information
Orudis is a NSAID, a nonsteroidal anti-inflammatory drug, is used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis (the most common form of arthritis). It is also used to relieve mild to moderate pain, as well as menstrual pain.Oruvail, an extended-release form of the drug, is used to treat the signs and symptoms of rheumatoid arthritis and osteoarthritis over the long term, not severe attacks that come on suddenly.
How to use
- Take Oruvail Extended-Release Capsules by mouth. It may be taken with food if it upsets your stomach. Taking it with food may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor or pharmacist if you have persistent stomach upset.
- Swallow Oruvail Extended-Release Capsules whole. Do not break, crush, or chew before swallowing.
- Take Oruvail Extended-Release Capsules with a full glass of water (8 oz/240 mL) as directed by your doctor.
Dosage
ADULTS
Rheumatoid Arthritis and Osteoarthritis
The starting dose of Orudis is 75 milligrams 3 times a day or 50 milligrams 4 times a day; for Oruvail, 200 milligrams taken once a day. The most you should take in a day is 300 milligrams of Orudis or 200 milligrams of Oruvail. Some side effects, such as headache or upset stomach, increase in severity as the dose gets higher.
Mild to Moderate Pain and Menstrual Pain
The usual dose of Orudis is 25 to 50 milligrams every 6 to 8 hours as needed.
Smaller people, older people, and those with kidney or liver disease need smaller doses of Orudis. Doses above 75 milligrams have no additional effect.
The usual dose of Actron or Orudis KT is 1 tablet or caplet (12.5 milligrams) every 4 to 6 hours. If you get no relief in 1 hour, you may take another tablet or caplet. Do not take more than 2 tablets or caplets in a 4 to 6-hour period. Do not take more than 6 tablets or caplets each 24 hours.
CHILDREN
Not for use in children under 16 years of age, unless recommended by a doctor.
OLDER ADULTS
Dosage may be lower.
Misdose
If you miss a dose of Oruvail Extended-Release Capsules and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.
Overdose
Any medication taken in excess can have serious consequences. If you suspect an overdose of Orudis, seek medical attention immediately.
Symptoms of Orudis overdose may include: Breathing difficulty, coma, convulsions, drowsiness, high blood pressure, kidney failure, low blood pressure, nausea, sluggishness, stomach and intestinal bleeding, stomach pain, vomiting
Side Effects
All medicines can cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach upset.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.
